For non-prescription products, read the label or package ingredients carefully. Amphetamine and dextroamphetamine combination works in the treatment of ADHD to increase attention and decrease restlessness in patients who are overactive, cannot concentrate, or are easily distracted. It is used as part of a total treatment program that also includes social, educational, and psychological therapy. Adderall® is a federally controlled substance (CII) because it can be abused or lead to dependence. Selling or giving away Adderall® may harm others, and is against the law. Adderall® is a central nervous system stimulant prescription medicine.
Adderall Withdrawal Side Effects
Adderall is a central nervous system stimulant prescription medicine. It is used for the treatment of attention-deficit hyperactivity disorder (ADHD). Adderall may help increase attention and decrease impulsiveness and hyperactivity in patients with ADHD. People who take Adderall for attention deficit hyperactivity disorder (ADHD) sometimes experience side effects when they first start the medication.
Adderall And Adderall XR (amphetamines) Information

ADDERALL is a federally controlled substance (CII) because it contains amphetamine that can be a target for people who abuse prescription medicines or street drugs. Never give your ADDERALL to anyone else because it may cause death or harm them. Selling or giving away ADDERALL may harm others and is against the law. Advise patients that there are potential risks to patients with serious cardiac disease, including sudden death, with ADDERALL use.
2 Risks To Patients With Serious Cardiac Disease
If you are trying to access this site from the United States, please try heading to our homepage or our drug directory. If those pages do not work and you believe you are receiving this message in error, please reach out to While it can be highly beneficial, it can also cause several side effects and can lead to addiction. Adderall has been known to cause stroke, heart problems, and sudden death in individuals with unresolved heart illness. Adderall instant release will typically last anywhere from 4 to 6 hours, while Adderall XR lasts 10 to 12 hours.
- Since amphetamine has a pKa of 9.9, urinary recovery of amphetamine is highly dependent on pH and urine flow rates.
- Also, a dose of Adderall is typically longer lasting than a dose of Ritalin.
- We aim to support the widest array of browsers and assistive technologies as possible, so our users can choose the best fitting tools for them, with as few limitations as possible.
- Since the FDA has not studied the use of Adderall IR in children younger than three years of age or of Adderall XR in children younger than six years of age, the FDA does not approve the use of Adderall XR in these younger age groups.
- Advise patients that ADDERALL may cause slowing of growth including weight loss see WARNINGS.
6 Agents That May Potentiate The Effects Of Amphetamines
When both amphetamine and methylphenidate are tried, the response rate rises to 88 percent. That means that one in every 12 people will not get the dramatic benefits that are usually seen with first-line ADHD medications. Before you give up hope and try alternative medications, you need to give the standard medications a full try. However, many women find that their ADHD medication is not as effective in the four to five days before their menstrual flow. Raising the dose of Adderall does not increase its level of benefits. Talk with your doctor about how to measure this loss of effectiveness.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter (OTC) medicines, herbal supplements (eg, St. John’s wort), and especially those for appetite control, asthma, colds, cough, hay fever, allergies, or sinus problems. Use with medications that increase stomach or urine alkalinity, including sodium bicarbonate should be avoided.
Common Adderall Side Effects
Norephedrine and 4-hydroxy-amphetamine are both active and each is subsequently oxidized to form 4-hydroxy-norephedrine. Alpha-hydroxy-amphetamine undergoes deamination to form phenylacetone, which ultimately forms benzoic acid and its glucuronide and the glycine conjugate hippuric acid. Although the enzymes involved in amphetamine metabolism have not been clearly defined, CYP2D6 is known to be involved with formation of 4-hydroxy-amphetamine. Since CYP2D6 is genetically polymorphic, population variations in amphetamine metabolism are a possibility.
If you’re having trouble opening medication bottles, ask your pharmacist about putting Adderall in an easy-open container. They also may recommend tools that can make it easier to open bottles. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech.
DRUG INTERACTIONS
- Kevin Ombisi, 31, and Eric Russell Jr., 35, were arrested on Thursday and made their initial court appearance on Friday.
- This was also the case in India, though these products remained a substantial part of the Indian market activity.
- Some patients feel that Adderall has less of a drop-off effect than Ritalin, which means fewer rebound side effects as the medication wears off.
- This medication should not be sold or shared; doing so is not only dangerous, but also illegal.
- In the USA, benzodiazepine prescription rates continue to increase (Bachhuber, Hennessy, Cunningham, & Starrels, 2016; Lembke, Papac, & Humphreys, 2018).
While not common, serious side effects have been reported with Adderall. Certain people may be at higher risk of these side effects based on other medical conditions they may have. Adderall was originally sold as an instant-release formulation, but in 2002 an extended-release alternative, known as Adderall XR, became available. The extended-release formulation produces effects that last between 10 and 12 hours, whereas the instant-release formulation’s effects last from about 4 to 8 hours. In both forms, Adderall functions by simulating the effects of naturally occurring chemicals in the brain, most notably the neurotransmitters dopamine and norepinephrine.

We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. Adderall is classified as a Category C drug for pregnancy, due to the lack of adequate studies in pregnant women. Inform your doctor if you are pregnant, as some research suggests that taking Adderall while pregnant may cause birth defects, according to the CDC. Additional research has found that dexamphetamine, one of the ingredients in Adderall, can transfer into breast milk. If you’re calling on behalf of someone else, stay with them until help arrives. You may remove weapons or substances that can cause harm if you can do so safely.

Adderall Vs Adderall XR Side Effects

The drug increases the activity of the brain chemicals dopamine and norepinephrine, according to the National Institute on Drug Abuse (NIDA). Adderall mainly stimulates the sympathetic nervous system, which triggers the body’s “fight or flight” responses, such as pupil dilation, increased blood pressure and heart rate and increased sweating. While Adderall is relatively safe if used as prescribed, misuse can quickly lead to dependence and addiction.
Drug Summary
You should not drink fruit juices such as orange juice within 1 hour of taking Adderall. Taking a medication with certain vaccines, foods, and other things can affect how the medication works. In some cases, misuse of Adderall may also lead to addiction (feeling unable to stop taking a drug, even though it may be causing harm). Adderall works by increasing the levels of certain neurotransmitters, norepinephrine and dopamine, in your brain. (Neurotransmitters are chemicals that help nerve cells communicate.) By increasing levels of these neurotransmitters, Adderall helps stimulate nerve activity in parts of the brain that are underactive. To learn more about how Adderall compares with other treatments for ADHD and narcolepsy, talk with your doctor.